What is Hezkue spray? Oral sildenafil spray for erectile dysfunction

We recommend always sticking to the prescribed dose.

3. Dosage Forms and Strengths

We recommend always sticking to the prescribed dose. If you think you need to be on a higher dose, speak to your clinician before increasing. The maximum safe daily dosage is 8 sprays (100mg). You are allergic to sildenafil (or any of the ingredients in Hezkue) You are taking medicines like nitrates or Riociguat as this may affect how they work You have had severe issues with your heart or liver Have loss of vision because of non-arteritic ischaemic optic neuropathy (NAION) To find out whether Hezkue may be suitable for you, contact our clinicians through your Account or reach out to our customer care team. Seek medical help right away if you are experiencing any of the above rare/serious side effects.

Can I get Hezkue on the NHS?

Side effects reported with sildenafil spray were generally mild and consistent with those seen in sildenafil tablets. In clinical studies, the product was generally well-tolerated. Always consult your healthcare provider if you have concerns. A full list of side effects will be available via the patient information leaflet within the packet. This will list other uncommon side effects and should be read prior to starting treatment. If you think you need to be on a higher dose, speak to your clinician before increasing. The maximum safe daily dosage is 8 sprays (100mg). You are allergic to sildenafil (or any of the ingredients in Hezkue) You are taking medicines like nitrates or Riociguat as this may affect how they work You have had severe issues with your heart or liver Have loss of vision because of non-arteritic ischaemic optic neuropathy (NAION) To find out whether Hezkue may be suitable for you, contact our clinicians through your Account or reach out to our customer care team.

• Sildenafil spray can enhance male sexual performance.
• It is often used when oral pills are not suitable.
• The spray allows for targeted delivery to the bloodstream.
• Rapid onset makes it suitable for spontaneous encounters.
• Use the spray exactly as directed by the healthcare professional.
• There is a risk of priapism with overuse.
• The spray may cause minor irritation at the application site.
• It is advisable to have medical supervision during use.
• The spray’s effectiveness depends on individual health.
• It is recommended to avoid alcohol for better results.
• Regular follow-up visits ensure safe use over time.

Seek medical help right away if you are experiencing any of the above rare/serious side effects. Side effects reported with sildenafil spray were generally mild and consistent with those seen in sildenafil tablets. In clinical studies, the product was generally well-tolerated.

Always consult your healthcare provider if you have concerns. A full list of side effects will be available via the patient information leaflet within the packet. This will list other uncommon side effects and should be read prior to starting treatment. Can you use a Sildenafil Suspension and Sildenafil tablets at the same time? Who is Sildenafil Suspension Spray suitable for?

Quick Summary

“When you’re choosing ED treatment think about what will suit your lifestyle the best. Not all treatments work on their first go. Combining ED medication with healthy lifestyle changes, having a health check with your GP and trying therapy for emotional or mental health causes can all improve your ED. Keep an open mind and we can help you find the most suitable treatment for you.” – Dr Sameer Sanghvi For more information on the possible side effects of Hezkue and correct use, please read the patient information leaflet. Please let your GP know if you experience any side effects while using Hezkue.

1. Delay sprays (lidocaine/benzocaine)

Like any treatment, you may experience side effects when taking Hezkue. Very common side effects (may affect more than 1 in 10 people) Common (may affect up to 1 in 10 people) Changes to sight (colour perception, blurred vision) Uncommon (may affect up to 1 in 100 people) Changes to heart rate and blood pressure Pain in upper abdomen, arms or legs Rare (may affect up to 1 in 1000 people) Changes to sight including spots in vision *Data based on mean plasma concentration after application of 8 pumps of HEZKUE®/BANDOL® (100 mg of sildenafil) compared to Viagra® tablets (100 mg sildenafil). Initial absorption of HEZKUE®/BANDOL® (100 mg of sildenafil) was observed within 5 minutes after administration (0.615 ng/mL, p = 0.012) vs Viagra® 100 mg tablets that showed no absorption at that time. It will be available other markets upon approval. Our initial product is a proprietary oral suspension formulation of sildenafil citrate, the active ingredient in VIAGRA® currently available in Spain as BANDOL® and available across all other geographies as HEZKUE®. How to choose between Sildenafil tablets and Sildenafil Suspension Hezkue, known as Bandol in Spain, is a Sildenafil Suspension. This is an oral erectile dysfunction spray you can use in place of a pill like Viagra. Once you have sprayed Hezkue into your mouth, it works like regular sildenafil in increasing blood flow to your penis by relaxing your muscle cells. This lets blood flow increase to your penis. Bear in mind that there are many different reasons you may have erectile dysfunction – Hezkue may not be able to help any psychological or emotional causes. Outline your medical history in our consultation and our clinicians will determine whether Hezkue is suitable for you. Initial tests have shown that, once applied orally, Hezkue was able to begin absorbing into the bloodstream within five minutes.

Frequently Asked Questions

Please visit our country specific websites below: Fast absorption after just 5 minutes compared to Viagra® tablets2* *Data based on mean plasma concentration after application of 8 pumps of HEZKUE®/BANDOL® (100 mg of sildenafil) compared to Viagra® tablets (100 mg sildenafil). Fast absorption after just 5 minutes compared to Viagra® tablets2* *Data based on mean plasma concentration after application of 8 pumps of HEZKUE®/BANDOL® (100 mg of sildenafil) compared to Viagra® tablets (100 mg sildenafil). With personalized dosing, HEZKUE®/BANDOL® is tailored to the users’ individual needs and lifestlyes and eliminates the need for planning.2 HEZKUE®/BANDOL® is bioequivalent to Viagra® tablets, offering a safe and effective alternative for treating ED.2 Delivers the same efficacious dose as Viagra®2* *Compared to Viagra® 100 mg tablets and well-established safety profile for sildenafil used in the treatment of ED. ** With respect to AUC, measured after application of 8 pumps of HEZKUE®/BANDOL® (100 mg of sildenafil) compared to Viagra® tablets (100 mg sildenafil). 2024.1 #Data based on mean plasma concentration after application of 8 pumps of HEZKUE®/BANDOL® (100 mg of sildenafil) compared to Viagra® tablets (100 mg sildenafil).

When should Silfin Oral Spray be taken?

Initial absorption of HEZKUE®/BANDOL® (100 mg of sildenafil) was observed within 5 minutes after administration (0.615 ng/mL) while Viagra® 100 mg tablets showed no absorption at that time.1 Viagra® (sildenafil) is a drug marketed in Spain by Viatris Pharmaceuticals S.L.( Initial absorption of HEZKUE®/BANDOL® was observed within 5 minutes after administration while Viagra® tablets showed no absorption at that time.1 Prospective, open-label, single-centre, two-way crossover comparative bioavailability study in 56 healthy male volunteers in fasting conditions. HEZKUE®/BANDOL® is bioequivalentto sildenafil tablets*2 HEZKUE®/BANDOL® is a safe and effective alternative for ED2 *The Pharmacokinetic study showed that HEZKUE®/BANDOL® was found bioequivalent to Viagra® tablet with respect to sildenafil systemic exposure, as reflected in the 90% confidence intervals for AUClast and AUC∞. HEZKUE®/BANDOL® and Viagra® tablet were not bioequivalent with respect to Cmax, with a modestly higher maximum sildenafil concentration for HEZKUE®/BANDOL®.1 Anti-Anxiety Medications, Anti-Depressants & Sleeping Pills5 In young men, it is usually undervalued and attributed to psychological problems6 HEZKUE®/BANDOL® is a ready-to-use sildenafil suspension spray. See HEZKUE®/BANDOL® product information (as of May 2024). Study UNICO: Perception of Urologists and Andrologists, in Spain, about the Use of Sildenail Oral Suspension in Patients with Erectile Dysfunction. When taken correctly, the effects of a Sildenafil Suspension can last up to five hours after use. However, this can depend on a number of different factors including: How many pumps of Hezkue you’ve taken How many pumps of Hezkue you’ve taken Please note that the ‘effects’ of a Sildenafil Suspension are the ability to get and maintain an erection. It doesn’t mean that you are likely to have one erection for five hours. Call 999 or attend A&E immediately if you have a prolonged or sometimes painful erection, especially if it lasts for more than 2 hours. Studies carried out by AspargoLabs have stated that Hezkue is as effective as a Sildenafil tablet – or its branded equivalent, Viagra. Clinical trials for Sildenafil showed that a standard dose (50mg) improved erections for 74% of patients that tried it. It is important liquid sildenafil citrate to note that some erectile dysfunction treatments may not work the first time, and it may take several times on different occasions for Hezkue to take effect. Before you use Hezkue for the first time, make sure you have performed three ‘practice pumps’ away from your mouth to make sure that the dosing pump is working properly. Once your pump is ready, do the following: Shake your bottle to help the Suspension mix Shake your bottle to help the Suspension mix Turn the pump to the left (making sure it’s open) Turn the pump to the left (making sure it’s open) Spray directly into the mouth several times – see recommended dosages below Spray directly into the mouth several times – see recommended dosages below Turn the pump back to the right to close Turn the pump back to the right to close This should only be done once on the day you plan to have an erection. Do not take a sildenafil tablet and a Sildenafil Suspension like Hezkue at the same time. This will not increase the chances of you getting an erection.

What is Hezkue Sildenafil Suspension?

However, this can depend on a number of different factors including: How many pumps of Hezkue you’ve taken How many pumps of Hezkue you’ve taken Please note that the ‘effects’ of a Sildenafil Suspension are the ability to get and maintain an erection. It doesn’t mean that you are likely to have one erection for five hours. Call 999 or attend A&E immediately if you have a prolonged or sometimes painful erection, especially if it lasts for more than 2 hours. Studies carried out by AspargoLabs have stated that Hezkue is as effective as a Sildenafil tablet – or its branded equivalent, Viagra. Clinical trials for Sildenafil showed that a standard dose (50mg) improved erections for 74% of patients that tried it.

Indications and Usage for Sildenafil Oral Suspension

It is important liquid sildenafil citrate to note that some erectile dysfunction treatments may not work the first time, and it may take several times on different occasions for Hezkue to take effect. Before you use Hezkue for the first time, make sure you have performed three ‘practice pumps’ away from your mouth to make sure that the dosing pump is working properly. Once your pump is ready, do the following: Shake your bottle to help the Suspension mix Shake your bottle to help the Suspension mix Turn the pump to the left (making sure it’s open) Turn the pump to the left (making sure it’s open) Spray directly into the mouth several times – see recommended dosages below Spray directly into the mouth several times – see recommended dosages below Turn the pump back to the right to close Turn the pump back to the right to close This should only be done once on the day you plan to have an erection. Do not take a sildenafil tablet and a Sildenafil Suspension like Hezkue at the same time. This will not increase the chances of you getting an erection. It will, however, increase the risk of you suffering from the side effects of sildenafil (see below). If you've tried Hezkue at this dose on at least six separate occasions, and you haven't found it effective, our clinicians may advise increasing to the maximum dose. Do not exceed the maximum recommended dose. Doing so increases the risk of experiencing potential side effects.

• Sildenafil spray utilizes absorption through oral mucosa.
• It provides a discreet alternative for erectile issues.
• Use the spray about 10-20 minutes before intimacy.
• It generally has fewer gastrointestinal side effects.
• The spray must be kept out of reach of children.
• Users should avoid alcohol to prevent adverse reactions.
• Compatibility with other medications should be checked.
• The spray may be part of a comprehensive ED treatment plan.
• Discontinue use and consult a doctor if adverse reactions occur.
• The spray’s effectiveness can improve confidence in men.
• Training on proper application enhances safety and effectiveness.

Hezkue is suitable for adult men who suffer from erectile dysfunction. You are allergic to sildenafil (or any of the ingredients in Hezkue) You are allergic to sildenafil (or any of the ingredients in Hezkue) You are taking medicines like nitrates or Riociguat as this may affect how they work You are taking medicines like nitrates or Riociguat as this may affect how they work You have had severe issues with your heart or liver You have had severe issues with your heart or liver For more information on whether Hezkue may be suitable for you, contact our clinicians through your Account or read the patient information leaflet. As Hezkue provides the same dose as a Viagra tablet and contains the same active ingredient, there isn’t a significant difference between the two treatments other than how they are administered. But if you’re unsure whether you’d prefer a spray over a tablet, keep the following in mind: Are you comfortable with ED pills (both psychologically and if you have any troubles with swallowing) Are you comfortable with ED pills (both psychologically and if you have any troubles with swallowing) Are you more likely to remember to carry a pill or Suspension bottle? Are you more likely to remember to carry a pill or Suspension bottle? Do you know a pill dosage that works for you or would you benefit from a flexible dosage? “When you’re choosing ED treatment think about what will suit your lifestyle the best. Not all treatments work on their first go. Combining ED medication with healthy lifestyle changes, having a health check with your GP and trying therapy for emotional or mental health causes can all improve your ED. Keep an open mind and we can help you find the most suitable treatment for you.” – Dr Sameer Sanghvi For more information on the possible side effects of Hezkue and correct use, please read the patient information leaflet.

Side Effects

3. Understand the Root Cause

Please let your GP know if you experience any side effects while using Hezkue. Like any treatment, you may experience side effects when taking Hezkue. Very common side effects (may affect more than 1 in 10 people) Common (may affect up to 1 in 10 people) Changes to sight (colour perception, blurred vision) Uncommon (may affect up to 1 in 100 people) Changes to heart rate and blood pressure Pain in upper abdomen, arms or legs Rare (may affect up to 1 in 1000 people) Changes to sight including spots in vision *Data based on mean plasma concentration after application of 8 pumps of HEZKUE®/BANDOL® (100 mg of sildenafil) compared to Viagra® tablets (100 mg sildenafil).

Initial absorption of HEZKUE®/BANDOL® (100 mg of sildenafil) was observed within 5 minutes after administration (0.615 ng/mL, p = 0.012) vs Viagra® 100 mg tablets that showed no absorption at that time. It will be available other markets upon approval. Our initial product is a proprietary oral suspension formulation of sildenafil citrate, the active ingredient in VIAGRA® currently available in Spain as BANDOL® and available across all other geographies as HEZKUE®. Please visit our country specific websites below: Fast absorption after just 5 minutes compared to Viagra® tablets2* *Data based on mean plasma concentration after application of 8 pumps of HEZKUE®/BANDOL® (100 mg of sildenafil) compared to Viagra® tablets (100 mg sildenafil). Fast absorption after just 5 minutes compared to Viagra® tablets2* *Data based on mean plasma concentration after application of 8 pumps of HEZKUE®/BANDOL® (100 mg of sildenafil) compared to Viagra® tablets (100 mg sildenafil). With personalized dosing, HEZKUE®/BANDOL® is tailored to the users’ individual needs and lifestlyes and eliminates the need for planning.2 HEZKUE®/BANDOL® is bioequivalent to Viagra® tablets, offering a safe and effective alternative for treating ED.2 Delivers the same efficacious dose as Viagra®2* *Compared to Viagra® 100 mg tablets and well-established safety profile for sildenafil used in the treatment of ED. ** With respect to AUC, measured after application of 8 pumps of HEZKUE®/BANDOL® (100 mg of sildenafil) compared to Viagra® tablets (100 mg sildenafil).

Impotence Spray vs. Other ED Treatments

It will, however, increase the risk of you suffering from the side effects of sildenafil (see below). If you've tried Hezkue at this dose on at least six separate occasions, and you haven't found it effective, our clinicians may advise increasing to the maximum dose. Do not exceed the maximum recommended dose. Doing so increases the risk of experiencing potential side effects. Hezkue is suitable for adult men who suffer from erectile dysfunction.

In Treatment of Erectile dysfunction

You are allergic to sildenafil (or any of the ingredients in Hezkue) You are allergic to sildenafil (or any of the ingredients in Hezkue) You are taking medicines like nitrates or Riociguat as this may affect how they work You are taking medicines like nitrates or Riociguat as this may affect how they work You have had severe issues with your heart or liver You have had severe issues with your heart or liver For more information on whether Hezkue may be suitable for you, contact our clinicians through your Account or read the patient information leaflet. As Hezkue provides the same dose as a Viagra tablet and contains the same active ingredient, there isn’t a significant difference between the two treatments other than how they are administered. But if you’re unsure whether you’d prefer a spray over a tablet, keep the following in mind: Are you comfortable with ED pills (both psychologically and if you have any troubles with swallowing) Are you comfortable with ED pills (both psychologically and if you have any troubles with swallowing) Are you more likely to remember to carry a pill or Suspension bottle? Are you more likely to remember to carry a pill or Suspension bottle? Do you know a pill dosage that works for you or would you benefit from a flexible dosage? 2024.1 #Data based on mean plasma concentration after application of 8 pumps of HEZKUE®/BANDOL® (100 mg of sildenafil) compared to Viagra® tablets (100 mg sildenafil). Initial absorption of HEZKUE®/BANDOL® (100 mg of sildenafil) was observed within 5 minutes after administration (0.615 ng/mL) while Viagra® 100 mg tablets showed no absorption at that time.1 Viagra® (sildenafil) is a drug marketed in Spain by Viatris Pharmaceuticals S.L.( Initial absorption of HEZKUE®/BANDOL® was observed within 5 minutes after administration while Viagra® tablets showed no absorption at that time.1 Prospective, open-label, single-centre, two-way crossover comparative bioavailability study in 56 healthy male volunteers in fasting conditions. HEZKUE®/BANDOL® is bioequivalentto sildenafil tablets*2 HEZKUE®/BANDOL® is a safe and effective alternative for ED2 *The Pharmacokinetic study showed that HEZKUE®/BANDOL® was found bioequivalent to Viagra® tablet with respect to sildenafil systemic exposure, as reflected in the 90% confidence intervals for AUClast and AUC∞.

6. Adverse Reactions/Side Effects

Can you use a Sildenafil Suspension and Sildenafil tablets at the same time? Who is Sildenafil Suspension Spray suitable for? How to choose between Sildenafil tablets and Sildenafil Suspension Hezkue, known as Bandol in Spain, is a Sildenafil Suspension. This is an oral erectile dysfunction spray you can use in place of a pill like Viagra. Once you have sprayed Hezkue into your mouth, it works like regular sildenafil in increasing blood flow to your penis by relaxing your muscle cells.

Sprays vs. Pills

This lets blood flow increase to your penis. Bear in mind that there are many different reasons you may have erectile dysfunction – Hezkue may not be able to help any psychological or emotional causes. Outline your medical history in our consultation and our clinicians will determine whether Hezkue is suitable for you. Initial tests have shown that, once applied orally, Hezkue was able to begin absorbing into the bloodstream within five minutes. When taken correctly, the effects of a Sildenafil Suspension can last up to five hours after use. HEZKUE®/BANDOL® and Viagra® tablet were not bioequivalent with respect to Cmax, with a modestly higher maximum sildenafil concentration for HEZKUE®/BANDOL®.1 Anti-Anxiety Medications, Anti-Depressants & Sleeping Pills5 In young men, it is usually undervalued and attributed to psychological problems6 HEZKUE®/BANDOL® is a ready-to-use sildenafil suspension spray. See HEZKUE®/BANDOL® product information (as of May 2024).

• Sildenafil spray offers a non-invasive alternative to injections.
• It promotes blood flow to the penile area.
• The onset of action is usually faster than tablets.
• It is an option for men who dislike swallowing pills.
• The spray may reduce gastrointestinal discomfort.
• Consistent use without medical advice is discouraged.
• Dose titration might be necessary for effectiveness.
• It may be used in combination with other ED treatments.
• Possible side effects include nasal congestion or dizziness.
• Proper storage extends the shelf life of the spray.
• Contact a healthcare provider if adverse effects occur.

Study UNICO: Perception of Urologists and Andrologists, in Spain, about the Use of Sildenail Oral Suspension in Patients with Erectile Dysfunction.