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Counsel patients that protective measures necessary to guard against sexually transmitted diseases, including the Human Immunodeficiency Virus (HIV), should be considered.Dose AdjustmentVardenafil orally disintegrating tablet is available only in a single strength. Patients who require a different dosage should be prescribed vardenafil film-coated tablets (LEVITRA).Manufactured for :Macleods Pharma USA, INC.Princeton, NJ 08540Manufactured by:Macleods Pharmaceutical Ltd.Daman (U.T.) INDIARevised: 01/2025 See FDA-approved patient labeling (Patient Information) Inform patients that vardenafil orally disintegrating tablet is not interchangeable with vardenafil film-coated tablets (LEVITRA) as it provides higher systemic exposure. They should also discuss that the maximum dosage is one vardenafil orally disintegrating tablet per 24 hours.

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Counsel patients that protective measures necessary to guard against sexually transmitted diseases, including the Human Immunodeficiency Virus (HIV), should be considered.Dose AdjustmentVardenafil orally disintegrating tablet is available only in a single strength. Patients who require a different dosage should be prescribed vardenafil film-coated tablets (LEVITRA).Manufactured for :Macleods Pharma USA, INC.Princeton, NJ 08540Manufactured by:Macleods Pharmaceutical Ltd.Daman (U.T.) INDIARevised: 01/2025 See FDA-approved patient labeling (Patient Information) Inform patients that vardenafil orally disintegrating tablet is not interchangeable with vardenafil film-coated tablets (LEVITRA) as it provides higher systemic exposure. They should also discuss that the maximum dosage is one vardenafil orally disintegrating tablet per 24 hours. Discuss with patients that vardenafil orally disintegrating tablet is contraindicated with regular and/or intermittent use of organic nitrates. Inform patients that vardenafil orally disintegrating tablet is contraindicated in patients who use guanylate cyclase stimulators, such as riociguat.

What are common drug interactions for vardenafil and tadalafil?

Discuss with patients the potential cardiac risk of sexual activity for patients with preexisting cardiovascular risk factors. Concomitant Use with Drugs which Lower Blood Pressure Inform patients that in some patients concomitant use of PDE5 inhibitors, including vardenafil orally disintegrating tablet, with alpha-blockers can lower blood pressure significantly leading to symptomatic hypotension (for example, fainting). Patients should be advised to contact the prescribing physician if other anti-hypertensive drugs or new medications that may interact with vardenafil orally disintegrating tablet are prescribed by another healthcare provider. Discuss with patients the appropriate use of vardenafil orally disintegrating tablet and its anticipated benefits. Patients should be advised to contact their healthcare provider if they are not satisfied with the quality of their sexual performance with vardenafil orally disintegrating tablet or in the case of an unwanted effect.

Graphical abstract

Advise patients to contact the prescribing physician if new medications that may interact with vardenafil orally disintegrating tablet are prescribed by another healthcare provider. Inform patients to stop use of all PDE5 inhibitors, including vardenafil orally disintegrating tablet, levitra professional generic and seek medical attention in the event of sudden loss of vision in one or both eyes. Physicians should also discuss with patients the increased risk of NAION among the general population in patients with a “crowded” optic disc, although evidence is insufficient to support screening of prospective users of PDE5 inhibitor, including vardenafil hydrochloride , for this uncommon condition[see Warnings and Precautions (5.4) and Adverse Reactions (6.1)]. Advise patients to stop taking PDE5 inhibitors, including vardenafil orally disintegrating tablet, and seek prompt medical attention in the event of sudden decrease or loss of hearing. It is not possible to determine whether these events are related directly to the use of PDE5 inhibitors or to other factors [see Adverse Reactions (6)]. Discuss with patients that vardenafil orally disintegrating tablet is contraindicated with regular and/or intermittent use of organic nitrates. Inform patients that vardenafil orally disintegrating tablet is contraindicated in patients who use guanylate cyclase stimulators, such as riociguat. Discuss with patients the potential cardiac risk of sexual activity for patients with preexisting cardiovascular risk factors. Concomitant Use with Drugs which Lower Blood Pressure Inform patients that in some patients concomitant use of PDE5 inhibitors, including vardenafil orally disintegrating tablet, with alpha-blockers can lower blood pressure significantly leading to symptomatic hypotension (for example, fainting). Patients should be advised to contact the prescribing physician if other anti-hypertensive drugs or new medications that may interact with vardenafil orally disintegrating tablet are prescribed by another healthcare provider. Discuss with patients the appropriate use of vardenafil orally disintegrating tablet and its anticipated benefits. Patients should be advised to contact their healthcare provider if they are not satisfied with the quality of their sexual performance with vardenafil orally disintegrating tablet or in the case of an unwanted effect. Advise patients to contact the prescribing physician if new medications that may interact with vardenafil orally disintegrating tablet are prescribed by another healthcare provider. Inform patients to stop use of all PDE5 inhibitors, including vardenafil orally disintegrating tablet, levitra professional generic and seek medical attention in the event of sudden loss of vision in one or both eyes. Physicians should also discuss with patients the increased risk of NAION among the general population in patients with a “crowded” optic disc, although evidence is insufficient to support screening of prospective users of PDE5 inhibitor, including vardenafil hydrochloride , for this uncommon condition[see Warnings and Precautions (5.4) and Adverse Reactions (6.1)]. Advise patients to stop taking PDE5 inhibitors, including vardenafil orally disintegrating tablet, and seek prompt medical attention in the event of sudden decrease or loss of hearing. It is not possible to determine whether these events are related directly to the use of PDE5 inhibitors or to other factors [see Adverse Reactions (6)]. Inform patients that vardenafil orally disintegrating tablet offers no protection against sexually transmitted diseases. Counsel patients that protective measures necessary to guard against sexually transmitted diseases, including the Human Immunodeficiency Virus (HIV), should be considered. Vardenafil orally disintegrating tablet is available only in a single strength. Patients who require a different dosage should be prescribed vardenafil film-coated tablets (LEVITRA).

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PATIENT INFORMATION FDA-approved patient labelingVardenafil(var-DEN-a-fil )Orally Disintegrating Tablets, 10 mgRead the Patient Information about vardenafil orally disintegrating tablet before you start taking it and again each time you get a refill. You may also find it helpful to share this information with your partner. This leaflet does not take the place of talking with your doctor. You and your doctor should talk about vardenafil orally disintegrating tablet when you start taking it and at regular checkups.

If you do not understand the information, or have questions, talk with your doctor or pharmacist.WHAT IMPORTANT INFORMATION SHOULD YOU KNOW ABOUT VARDENAFIL ORALLY DISINTEGRATING TABLETS?Vardenafil orally disintegrating tablet is not interchangeable with vardenafil film-coated tablets (LEVITRA).

Our approach to erectile dysfunction

Sexual activity can put an extra strain on your heart, especially if your heart is already weak from a heart attack or heart disease.WHAT SHOULD YOU DISCUSS WITH YOUR DOCTOR BEFORE TAKING VARDENAFIL ORALLY DISINTEGRATING TABLETS?Before taking vardenafil orally disintegrating tablet, tell your doctor about all your medical problems, including if you:Have heart problems such as angina, heart failure, irregular heartbeats, or have had a heart attack. Ask your doctor if it is safe for you to have sexual activity.Have low blood pressure or have high blood pressure that is not controlled.Have pulmonary hypertensionHave had a stroke.Have had a seizure.Or any family members have a rare heart condition known as prolongation of the QT interval (long QT syndrome).Have liver problems.Have kidney problems and require dialysis.Have retinitis pigmentosa, a rare genetic (runs in families) eye disease.Have ever had severe vision loss, or if you have an eye condition called non-arteritic anterior ischemic optic neuropathy (NAION).Have stomach ulcers.Have a bleeding problem.Have a deformed penis shape or Peyronie’s disease.Have had an erection that lasted more than 4 hours.Have blood cell problems such as sickle cell anemia, multiple myeloma, or leukemia.Have hearing problems.Have phenylketonuria.Have fructose intolerance.CAN OTHER MEDICATIONS AFFECT VARDENAFIL ORALLY DISINTEGRATING TABLET?Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

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Vardenafil orally disintegrating tablet can cause your blood pressure to drop suddenly to an unsafe level if it is taken with certain other medicines.

What should I know about storage and disposal of this medication?

With a sudden drop in blood pressure, you could get dizzy, faint, or have a heart attack or stroke. Vardenafil orally disintegrating tablet contains phenylalanine which can be harmful to people who have phenylketonuria. Talk to your doctor if you have phenylketonuria.Do not take vardenafil orally disintegrating tablet if you:•Take any medicines called "nitrates" (often used to control chest pain, also known as angina)•Use recreational drugs called "poppers" like amyl nitrate and butyl nitrate.•Take riociguat (Adempas®), a guanulate cyclase stimulator, a medicine that treats pulmonary arterial hypertension and chronic-thromboembolic pulmonary hypertension. (See "Who levitra woman Should Not Take Vardenafil Orally Disintegrating Tablet?

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If you need emergency medical care for a heart problem, it will be important for your healthcare provider to know when you last took vardenafil orally disintegrating tablet.WHAT IS vardenafil orally disintegrating tablet?Vardenafil orally disintegrating tablet is a prescription medicine taken by mouth for the treatment of erectile dysfunction (ED) in men.ED is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. A man who has trouble getting or keeping an erection should see his doctor for help if the condition bothers him. Vardenafil orally disintegrating tablet may help a man with ED get and keep an erection when he is sexually excited.Vardenafil orally disintegrating tablet does not:•Cure ED.•Increase a man’s sexual desire.•Protect a man or his partner from sexually transmitted diseases, including HIV. Speak to your doctor about ways to guard against sexually transmitted diseases.•Serve as a male form of birth control.Vardenafil orally disintegrating tablet is only for men with ED. Vardenafil orally disintegrating tablet is not for women or children.

Contribution of sewage to occurrence of phosphodiesterase-5 inhibitors in natural water

Vardenafil orally disintegrating tablet must be used only under a doctor's care.HOW DOES VARDENAFIL ORALLY DISINTEGRATING TABLETS WORK?When a man is sexually stimulated, his body’s normal physical response is to increase blood flow to his penis. This results in an erection vardenafil orally disintegrating tablet helps increase blood flow to the penis and may help men with ED get and keep an erection satisfactory for sexual activity. Once a man has completed sexual activity, blood flow to his penis decreases, and his erection goes away.WHO CAN TAKE VARDENAFIL ORALLY DISINTEGRATING TABLETS?Talk to your doctor to decide if vardenafil orally disintegrating tablet is right for you.Vardenafil orally disintegrating tablet has been shown to be effective in men over the age of 18 years who have erectile dysfunction, including men with diabetes.WHO SHOULD NOT TAKE VARDENAFIL ORALLY DISINTEGRATING TABLETS?Do not take Vardenafil orally disintegrating tablet if you:Take any medicines called “nitrates” (see “What important information should you know about vardenafil orally disintegrating tablet?”). Nitrates are commonly used to treat angina. Angina is a symptom of heart levitra oral jelly uk disease and can cause pain in your chest, jaw, or down your arm.

Psychological conditions

Medicines called nitrates include nitroglycerin that is found in tablets, sprays, ointments, pastes, or patches. Nitrates can also be found in other medicines such as isosorbide dinitrate or isosorbide mononitrate. Some recreational drugs called “poppers” also contain nitrates, such as amyl nitrate and butyl nitrate. Do not use vardenafil orally disintegrating tablet if you are using these drugs. Ask your doctor or pharmacist if you are not sure if any of your medicines are nitrates.Take riociguat, a guanylate cyclase stimulator, a medicine that treats pulmonary arterial hypertension and chronic-thrombotic pulmonary hypertension.Have been told by your healthcare provider to not have sexual activity because of health problems. ")Tell all your healthcare providers that you take vardenafil orally disintegrating tablet.

Brand names

If you need emergency medical care for a heart problem, it will be important for your healthcare provider to know when you last took vardenafil orally disintegrating tablet.WHAT IS vardenafil orally disintegrating tablet?Vardenafil orally disintegrating tablet is a prescription medicine taken by mouth for the treatment of erectile dysfunction (ED) in men.ED is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. A man who has trouble getting or keeping an erection should see his doctor for help if the condition bothers him. Vardenafil orally disintegrating tablet may help a man with ED get and keep an erection when he is sexually excited.Vardenafil orally disintegrating tablet does not:•Cure ED.•Increase a man’s sexual desire.•Protect a man or his partner from sexually transmitted diseases, including HIV. Speak to your doctor about ways to guard against sexually transmitted diseases.•Serve as a male form of birth control.Vardenafil orally disintegrating tablet is only for men with ED.

Vardenafil orally disintegrating tablet is not for women or children.

8.7 Renal Impairment

Inform patients that vardenafil orally disintegrating tablet offers no protection against sexually transmitted diseases. Counsel patients that protective measures necessary to guard against sexually transmitted diseases, including the Human Immunodeficiency Virus (HIV), should be considered. Vardenafil orally disintegrating tablet is available only in a single strength. Patients who require a different dosage should be prescribed vardenafil film-coated tablets (LEVITRA). PATIENT INFORMATION FDA-approved patient labelingVardenafil(var-DEN-a-fil )Orally Disintegrating Tablets, 10 mgRead the Patient Information about vardenafil orally disintegrating tablet before you start taking it and again each time you get a refill.

Environ. Health Perspect.

You may also find it helpful to share this information with your partner. This leaflet does not take the place of talking with your doctor. You and your doctor should talk about vardenafil orally disintegrating tablet when you start taking it and at regular checkups. If you do not understand the information, or have questions, talk with your doctor or pharmacist.WHAT IMPORTANT INFORMATION SHOULD YOU KNOW ABOUT VARDENAFIL ORALLY DISINTEGRATING TABLETS?Vardenafil orally disintegrating tablet is not interchangeable with vardenafil film-coated tablets (LEVITRA). Vardenafil orally disintegrating tablet can cause your blood pressure to drop suddenly to an unsafe level if it is taken with certain other medicines.

Hormonal changes

With a sudden drop in blood pressure, you could get dizzy, faint, or have a heart attack or stroke. Vardenafil orally disintegrating tablet contains phenylalanine which can be harmful to people who have phenylketonuria. Talk to your doctor if you have phenylketonuria.Do not take vardenafil orally disintegrating tablet if you:•Take any medicines called "nitrates" (often used to control chest pain, also known as angina)•Use recreational drugs called "poppers" like amyl nitrate and butyl nitrate.•Take riociguat (Adempas®), a guanulate cyclase stimulator, a medicine that treats pulmonary arterial hypertension and chronic-thromboembolic pulmonary hypertension. (See "Who levitra woman Should Not Take Vardenafil Orally Disintegrating Tablet? ")Tell all your healthcare providers that you take vardenafil orally disintegrating tablet. Vardenafil orally disintegrating tablet must be used only under a doctor's care.HOW DOES VARDENAFIL ORALLY DISINTEGRATING TABLETS WORK?When a man is sexually stimulated, his body’s normal physical response is to increase blood flow to his penis. This results in an erection vardenafil orally disintegrating tablet helps increase blood flow to the penis and may help men with ED get and keep an erection satisfactory for sexual activity. Once a man has completed sexual activity, blood flow to his penis decreases, and his erection goes away.WHO CAN TAKE VARDENAFIL ORALLY DISINTEGRATING TABLETS?Talk to your doctor to decide if vardenafil orally disintegrating tablet is right for you.Vardenafil orally disintegrating tablet has been shown to be effective in men over the age of 18 years who have erectile dysfunction, including men with diabetes.WHO SHOULD NOT TAKE VARDENAFIL ORALLY DISINTEGRATING TABLETS?Do not take Vardenafil orally disintegrating tablet if you:Take any medicines called “nitrates” (see “What important information should you know about vardenafil orally disintegrating tablet?”).

Nitrates are commonly used to treat angina. Angina is a symptom of heart levitra oral jelly uk disease and can cause pain in your chest, jaw, or down your arm. Medicines called nitrates include nitroglycerin that is found in tablets, sprays, ointments, pastes, or patches. Nitrates can also be found in other medicines such as isosorbide dinitrate or isosorbide mononitrate.

Some recreational drugs called “poppers” also contain nitrates, such as amyl nitrate and butyl nitrate.

Country or Region Approval Status Regulatory Body Availability Notes
United States Approved by FDA Food and Drug Administration Prescription-only Classified as prescription medication
European Union Approved in several countries EMA Prescription-only Must adhere to local regulations
Canada Approved by Health Canada Health Canada Prescription-only Controlled substance
Australia Approved by TGA Therapeutic Goods Administration Prescription-only Requires prescription

Do not use vardenafil orally disintegrating tablet if you are using these drugs.

What are the differences between vardenafil and tadalafil?

Ask your doctor or pharmacist if you are not sure if any of your medicines are nitrates.Take riociguat, a guanylate cyclase stimulator, a medicine that treats pulmonary arterial hypertension and chronic-thrombotic pulmonary hypertension.Have been told by your healthcare provider to not have sexual activity because of health problems.

Precaution/Contraindication Explanation Alternatives or Actions
Use with nitrate medications Can cause severe hypotension Consult doctor before use
Heart conditions Risk of cardiovascular events Medical evaluation recommended
Liver or kidney impairment Affects drug metabolism Dose adjustment needed
Allergies to ingredients Risk of allergic reactions Check ingredient list

Sexual activity can put an extra strain on your heart, especially if your heart is already weak from a heart attack or heart disease.WHAT SHOULD YOU DISCUSS WITH YOUR DOCTOR BEFORE TAKING VARDENAFIL ORALLY DISINTEGRATING TABLETS?Before taking vardenafil orally disintegrating tablet, tell your doctor about all your medical problems, including if you:Have heart problems such as angina, heart failure, irregular heartbeats, or have had a heart attack. Ask your doctor if it is safe for you to have sexual activity.Have low blood pressure or have high blood pressure that is not controlled.Have pulmonary hypertensionHave had a stroke.Have had a seizure.Or any family members have a rare heart condition known as prolongation of the QT interval (long QT syndrome).Have liver problems.Have kidney problems and require dialysis.Have retinitis pigmentosa, a rare genetic (runs in families) eye disease.Have ever had severe vision loss, or if you have an eye condition called non-arteritic anterior ischemic optic neuropathy (NAION).Have stomach ulcers.Have a bleeding problem.Have a deformed penis shape or Peyronie’s disease.Have had an erection that lasted more than 4 hours.Have blood cell problems such as sickle cell anemia, multiple myeloma, or leukemia.Have hearing problems.Have phenylketonuria.Have fructose intolerance.CAN OTHER MEDICATIONS AFFECT VARDENAFIL ORALLY DISINTEGRATING TABLET?Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

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